Functional and phylogenetic analysis Fgf8 shows that Fgf8 is not involved in external genital development
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چکیده
منابع مشابه
Functional and phylogenetic analysis shows that Fgf8 is a marker of genital induction in mammals but is not required for external genital development.
In mammalian embryos, male and female external genitalia develop from the genital tubercle. Outgrowth of the genital tubercle is maintained by the urethral epithelium, and it has been reported that Fgf8 mediates this activity. To test directly whether Fgf8 is required for external genital development, we conditionally removed Fgf8 from the cloacal/urethral epithelium. Surprisingly, Fgf8 is not ...
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ژورنال
عنوان ژورنال: Developmental Biology
سال: 2009
ISSN: 0012-1606
DOI: 10.1016/j.ydbio.2009.05.419